Ciro Motionless returns to the beginning XI as Lazio attempt to get again on monitor towards a Cagliari aspect coming off three consecutive defeats.
It kicks off on the Unipol Domus enviornment at 14.00 GMT.
The Aquile have stuttered over the previous couple of weeks, crashing 3-0 to Inter within the Supercoppa Italiana, then held by Napoli and shedding 3-1 to Atalanta in Serie A.
Nicolò Rovella is suspended, with Mattia Zaccagni and Patric nonetheless on the therapy desk, however the excellent news is the return of Motionless to the beginning XI, with Gustav Isaksen and Felipe Anderson finishing the trident.
Cagliari have misplaced three on the bounce and are sliding down the standings, particularly after Empoli beat Salernitana 3-1 final evening.
Pantelis Hatzidiakos is out for a month with a knee damage, becoming a member of Ibrahim Sulemana, Marco Mancosu, Gaetano Oristanio and Eldor Shomurodov on the sidelines.
January signing Yerry Mina is confirmed in defence, with Nicolas Viola supporting Gianluca Lapadula.
Cagliari: Scuffet; Zappa, Mina, Obert; Nandez, Makoumbou, Deiola, Gaetano, Azzi; Viola; Lapadula
Lazio: Provedel; Marusic, Gila, Romagnoli, Hysaj; Guendouzi, Cataldi, Luis Alberto; Felipe Anderson, Motionless, Isaksen